CSR Biotech MI-SIM

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CSR Biotech MI-SIM
Overview
Highlights
1. 2D/3D Realtime Super Resolution - First to realize real-time SR imaging, seeing is obtaining
The Real-time SR helps to rapidly localize the distribution of cristae within mitochondria.
2. 60 nm Super Resolution - First to achieve 60 nm resolution in live-cell imaging with extremely low photobleaching
First in the world to capture the 60 nm ring of NUP98 in a live cell and its dynamics
3. Long-term Live-cell Tracking - World's 1st to realize real-time intelligent tracking for long-term live cell imaging
Long-term tracking of protein and mitochondria dynamics during U2OS cell apoptosis while maintaining the center of the field of view unchanged and in focus
MI-SIM (Machine Intelligent-Structured Illumination Microscope) represents a comprehensive super-resolution microscopy solution for live cell imaging, entirely conceived, developed, produced, and marketed by CSR Biotech. This advanced technology was born from the collaborative efforts of an interdisciplinary team at Peking University, renowned for their groundbreaking work in biomedical imaging. As a tool of choice, MI-SIM offers exceptional capabilities for observing live cell dynamics with ultra-high spatial and temporal resolution.
With its exceptional spatial resolution surpassing 60 nm, swift imaging capabilities reaching up to 1500 frames per second, and an expansive field of view (FOV) of 150 μm with a 100 × objective, the MI-SIM sets new standards in 3D super-resolution imaging of various dynamic processes in living cells. Notably, MI-SIM's advanced sensitivity and reduced photo-toxicity facilitate prolonged imaging sessions while minimizing photobleaching effects.
MI-SIM boasts a suite of sophisticated features, including real-time super-resolution, multi-camera and multi-site imaging capabilities, and intelligent region-of-interest (ROI) planning. It also excels in stitching within large FOV, 3D real-time tracking, multimodal focusing, and event-driven tracking. These capabilities underscore MI-SIM's versatility, ease of use, and user-centric design, reflecting CSR Biotech's leadership in the realms of advanced imaging, online decision-making, and intelligent control systems.
CSR Biotech- link to website
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